Alzheimer yare no ano aduru biara nni hɔ, nanso nyansahufo rehwehwɛ akwan a wɔbɛfa so asa yare no ho sɛnkyerɛnne ahorow no mu daa.
Nhwehwɛmufo nso reyɛ adwuma de ahu adwenemhaw a ɛbata Alzheimer yare no ho ntɛm, efisɛ sɛ wohu ntɛm a, ebetumi aboa wɔ ayaresa mu.
Nhwehwɛmu foforo bi a wotintimii wɔ Frontiers in Aging Neuroscience mu kyerɛ sɛ formic acid a ɛwɔ nsu mu betumi ayɛ biomarker a ebetumi ayɛ biomarker a ɛbɛma wɔahu Alzheimer yare no ntɛm.
U.S. Asoɛe a Ɛhwɛ Nyarewa So (CDC) ka adwenemhaw ho asɛm sɛ “nkae, nsusuwii, anaa gyinaesi a ɛyɛ mmerɛw a esiw da biara da dwumadi ahorow kwan.”
Alzheimer yare no akyi no, adwenemhaw afoforo te sɛ adwenemhaw a ɛwɔ Lewy nipadua ne ntini mu adwenemhaw. Nanso Alzheimer yare ne adwenemhaw a abu so sen biara.
Sɛnea Alzheimer Yare Fekuw no amanneɛbɔ a ɛbaa afe 2022 mu kyerɛ no, nnipa bɛyɛ ɔpepem 6.5 na wɔde yare no te ase wɔ United States. Bio nso, nhwehwɛmufo hwɛ kwan sɛ ebedu afe 2050 no, saa dodow no bɛboro mmɔho abien.
Nea ɛka ho no, ebetumi ayɛ den ama nnipa a wɔwɔ Alzheimer yare a emu yɛ den no sɛ wɔbɛmene, wɔbɛkasa, na wɔnantew.
Ɛde besi 2000 mfe no mfiase no, na funu mu nhwehwɛmu nkutoo ne ɔkwan a wɔfa so si so dua sɛ ebia obi wɔ Alzheimer yare anaasɛ adwenemhaw foforo bi.
Sɛnea Ɔman Asoɛe a Ɛhwɛ Mpanyinyɛ So kyerɛ no, mprempren nnuruyɛfo betumi ayɛ akyi berɛmo mu akuturuku, a wɔsan frɛ no akyi berɛmo mu akuturuku, de ahwɛ sɛ ebia biomarkers a ɛne Alzheimer yare no wɔ abusuabɔ anaa.
Nnuruyɛfo hwehwɛ biomarkers te sɛ beta-amyloid 42, ade titiriw a ɛwɔ amyloid plaques a ɛwɔ amemene no mu, na ebia wɔbɛhwehwɛ nneɛma a ɛnteɛ wɔ PET scan mu.
Michigan Sukuupɔn mu akwahosan ho ɔbenfo ne oduruyɛfo Kenneth M. Oduruyɛfo Langa kae sɛ: “Mfoniniyɛ akwan foforo, titiriw amyloid mfoninitwa, amyloid PET mfoninitwa, ne tau PET mfoninitwa, ma yetumi hu nneɛma a ɛnteɛ wɔ amemene no mu bere a obi te ase.” wɔ Ann Arbor, a na ɔmfa ne ho nhyɛ nhwehwɛmu no mu no kaa Michigan Medicine podcast bi a wɔyɛe nnansa yi ho asɛm.
Ayaresa ahorow bi betumi aboa ma ayamtu ho sɛnkyerɛnne a emu yɛ den no so atew na ama yare no akɔ so brɛoo, ɛwom sɛ wontumi nsa de.
Sɛ nhwɛso no, oduruyɛfo betumi akyerɛw nnuru te sɛ donepezil anaa galantamine de atew ayamtu ho sɛnkyerɛnne so. Aduru bi a wɔde yɛ nhwehwɛmu a wɔfrɛ no lecanemab nso betumi ama Alzheimer yare no akɔ so brɛoo.
Esiane sɛ nhwehwɛmu a wɔyɛ de hu Alzheimer yare no bo yɛ den na ebia obiara rentumi nyɛ saa nti, nhwehwɛmufo binom de nhwehwɛmu a wɔbɛyɛ ntɛm no redi kan.
Nhwehwɛmufo a wofi Shanghai Jiaotong Sukuupɔn ne WuXi Institute of Diagnostic Innovation of China boom yɛɛ dwuma a formic acid di sɛ Alzheimer yare no ho sɛnkyerɛnne wɔ nsu mu no mu nhwehwɛmu.
Nyansahufo no gyinaa Alzheimer yare no biomarker nhwehwɛmu ahorow a atwam so paw saa aduru pɔtee yi. Wɔhyɛ no nsow sɛ formaldehyde a ɛnyɛ ne kwan so a ɛsakra no yɛ ade titiriw a ɛma obi ntumi nhu ade yiye esiane mfe a obi adi nti.
Wɔ nhwehwɛmu yi mu no, akyerɛwfo no faa nnipa 574 a wɔde wɔn ho hyɛɛ mu fii Memory Clinic a ɛwɔ Sixth People’s Hospital of Shanghai, China, no mu.
Wɔkyekyɛɛ wɔn a wɔde wɔn ho hyɛɛ mu no mu akuw anum a egyina sɛnea wɔyɛɛ adwuma wɔ nkate mu dwumadi ho sɔhwɛ ahorow mu so; na akuw yi fi adwene a ɛfata so kosi Alzheimer yare so:
Nhwehwɛmufo no boaboaa nsu a wɔde yɛɛ nhwehwɛmu fii wɔn a wɔde wɔn ho hyɛɛ mu no hɔ de hwehwɛɛ formic acid dodow ne mogya mu de yɛɛ DNA nhwehwɛmu.
Ɛdenam formic acid dodow a wɔde totoo kuw biara ho so no, nhwehwɛmufo no huu nsonsonoe wɔ wɔn a wɔde wɔn ho hyɛɛ mu a wɔwɔ adwene mu apɔwmuden ne wɔn a anyɛ yiye koraa no wɔn adwene mu yɛ wɔn naa kodu baabi no ntam.
Wɔ akuw a wɔn adwene so atew kodu baabi mu no, na formic acid dodow a ɛwɔ nsu mu no dɔɔso sen akuw a wɔn adwene mu dwumadi ahorow a ɛyɛ papa no.
Afei nso, na wɔn a wɔde wɔn ho hyɛɛ mu a wɔwɔ Alzheimer yare no wɔ formic acid dodow a ɛkɔ soro kɛse wɔ wɔn nsu mu sen wɔn a wɔde wɔn ho hyɛɛ mu a wɔwɔ adwene mu apɔwmuden no.
Nyansahufo no nso huu abusuabɔ bɔne bi a ɛda formic acid dodow a ɛwɔ nsu mu ne adwene mu sɔhwɛ ahorow a wɔyɛ wɔ mmeae a wɔkae ade ne adwene a wɔde si biribi so no ntam.
Nhoma akyerɛwfo no kyerɛw sɛ: “Ná UA kɔɔ soro kɛse wɔ kuw a wohu [adwene a ɛkɔ fam wɔ adwene mu] no mu, a ɛkyerɛ sɛ wobetumi de UA adi dwuma de ahu [Alzheimer yare] ntɛm.”
Nea afi nhwehwɛmu yi mu aba no ho hia esiane nneɛma pii nti, na ɛnyɛ nea ɛsen biara no, ɛka kɛse a wɔbɔ de hu Alzheimer yare no.
Sɛ nhwehwɛmu foforo kyerɛ sɛ urine formate tumi hu sɛ adwene mu nneɛma so tew a, eyi betumi abɛyɛ sɔhwɛ a ɛnyɛ den sɛ wɔde bedi dwuma na ne bo nyɛ den.
Nea ɛka ho no, sɛ sɔhwɛ a ɛte saa betumi ahu adwene mu ɔhaw a ɛbata Alzheimer yare no ho a, akwahosan ho adwumayɛfo betumi de wɔn ho agye mu ntɛmntɛm.
Oduruyɛfo Sandra Petersen, DNP, akwahosan ne yiyedi ho ɔmampanyin abadiakyiri panyin wɔ Pegasus Senior Living, kaa nhwehwɛmu no ho asɛm kyerɛɛ Medical News Today sɛ:
“Nsakrae a ɛba wɔ Alzheimer yare mu no fi ase bɛyɛ mfe 20 kosi 30 ansa na wɔahu sɛ obi anya bi na mpɛn pii no wonhu kosi sɛ ɛbɛsɛe kɛse.Yenim sɛ sɛ wohu ntɛm a, ebetumi ama ayarefo anya ayaresa pii a wobetumi apaw na wɔatumi ayɛ nhyehyɛe ama daakye ɔhwɛ.”
Oduruyɛfo Peterson kae sɛ: “Nkɔso a wobenya wɔ sɔhwɛ a ɛte saa (a ɛnyɛ nea wɔde hyɛ nipadua mu na ne bo nyɛ den) a ɔmanfo nyinaa betumi anya mu no bɛyɛ agoru a ɛbɛsakra ade wɔ Alzheimer yare a wɔko tia no mu.”
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Ebia da bi aniwa mu nhwehwɛmu a wɔyɛ no ntɛm bɛma wɔanya amemene no akwahosan ho nsɛm a ɛho hia. Titiriw no, etumi hu sɛnkyerɛnne ahorow a ɛkyerɛ sɛ obi anya adwenemhaw.